Which glucocorticoid is involved in glucose metabolism and can be stimulated under stress?

Cortisol is the glucocorticoid that plays a vital role in glucose metabolism and is released in response to stress. It is often referred to as the "stress hormone" because its secretion increases significantly during stressful situations, such as physical or emotional stress. The primary functions of cortisol include increasing blood glucose levels through gluconeogenesis in the liver, enhancing the breakdown of fats, and reducing the uptake of glucose by certain tissues, which makes more glucose available for the brain and other vital organs during times of stress.

Cortisol also helps regulate various metabolic processes and maintains homeostasis within the body. Its action on glucose metabolism is crucial for energy production, particularly during stressful events when the body requires additional energy. Understanding the role of cortisol enhances comprehension of the body's physiological response to stress and the broader implications for metabolism and health.