What is the primary function of the zona pellucida?

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The primary function of the zona pellucida is to bind sperm for fertilization. This glycoprotein layer surrounds the oocyte and plays a critical role in the fertilization process. When sperm encounter the zona pellucida, specific sperm receptors on the surface of the sperm recognize and bind to proteins in the zona pellucida. This binding initiates a series of reactions that allow the sperm to penetrate the zona pellucida and ultimately facilitate fertilization of the egg. The zona pellucida not only ensures that only sperm of the same species can fertilize the egg but also helps protect the egg until the appropriate time for fertilization.

In contrast, other functions attributed to the zona pellucida are not its primary role. It does not primarily provide nutrients to the embryo, as that function is typically carried out by surrounding maternal tissues or the placenta after implantation. While the zona pellucida plays a role in the later stages of implantation, it does not initiate this process directly. Lastly, while it has protective qualities, its principal function is not focused on protection against pathogens.

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